Dual histone methyl reader ZCWPW1 facilitates repair of meiotic double strand breaks in male mice

Meiotic crossovers result from homology-directed repair of DNA double-strand breaks (DSBs). Unlike yeast and plants, where DSBs are generated near gene promoters, in many vertebrates DSBs are enriched at hotspots determined by the DNA binding activity of the rapidly evolving zinc finger array of PRD...

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Detalles Bibliográficos
Autores principales: Mahgoub, Mohamed, Paiano, Jacob, Bruno, Melania, Wu, Wei, Pathuri, Sarath, Zhang, Xing, Ralls, Sherry, Cheng, Xiaodong, Nussenzweig, André, Macfarlan, Todd S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237205/
https://www.ncbi.nlm.nih.gov/pubmed/32352380
http://dx.doi.org/10.7554/eLife.53360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237205/
https://www.ncbi.nlm.nih.gov/pubmed/32352380
http://dx.doi.org/10.7554/eLife.53360

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