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Zebrafish macrophage developmental arrest underlies depletion of microglia and reveals Csf1r-independent metaphocytes

Macrophages derive from multiple sources of hematopoietic progenitors. Most macrophages require colony-stimulating factor 1 receptor (CSF1R), but some macrophages persist in the absence of CSF1R. Here, we analyzed mpeg1:GFP–expressing macrophages in csf1r-deficient zebrafish and report that embryoni...

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Detalles Bibliográficos
Autores principales: Kuil, Laura E, Oosterhof, Nynke, Ferrero, Giuliano, Mikulášová, Tereza, Hason, Martina, Dekker, Jordy, Rovira, Mireia, van der Linde, Herma C, van Strien, Paulina MH, de Pater, Emma, Schaaf, Gerben, Bindels, Erik MJ, Wittamer, Valerie, van Ham, Tjakko J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237208/
https://www.ncbi.nlm.nih.gov/pubmed/32367800
http://dx.doi.org/10.7554/eLife.53403