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OTX2 represses sister cell fate choices in the developing retina to promote photoreceptor specification

During vertebrate retinal development, subsets of progenitor cells generate progeny in a non-stochastic manner, suggesting that these decisions are tightly regulated. However, the gene-regulatory network components that are functionally important in these progenitor cells are largely unknown. Here w...

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Detalles Bibliográficos
Autores principales: Ghinia Tegla, Miruna Georgiana, Buenaventura, Diego F, Kim, Diana Y, Thakurdin, Cassandra, Gonzalez, Kevin C, Emerson, Mark M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237216/
https://www.ncbi.nlm.nih.gov/pubmed/32347797
http://dx.doi.org/10.7554/eLife.54279