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Germline genetic variation in prostate susceptibility does not predict outcomes in the chemoprevention trials PCPT and SELECT

BACKGROUND: The development of prostate cancer can be influenced by genetic and environmental factors. Numerous germline SNPs influence prostate cancer susceptibility. The functional pathways in which these SNPs increase prostate cancer susceptibility are unknown. Finasteride is currently not being...

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Detalles Bibliográficos
Autores principales: Ahmed, Mahbubl, Goh, Chee, Saunders, Edward, Cieza-Borrella, Clara, Kote-Jarai, Zsofia, Schumacher, Fredrick R., Eeles, Ros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237354/
https://www.ncbi.nlm.nih.gov/pubmed/31776447
http://dx.doi.org/10.1038/s41391-019-0181-y