Aggregation of M3 (E376D) variant of alpha1- antitrypsin

Alpha1-antitrypsin (α1AT) is an abundant serine-protease inhibitor in circulation. It has an important role in neutralizing the neutrophil elastase activity. Different pathogenic point mutations like Z((E342K))-α1AT have been implicated in the development of liver cirrhosis and Chronic Obstructive P...

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Detalles Bibliográficos
Autores principales: Bashir, Arif, Hazari, Younis, Pal, Debnath, Maity, Dibyajyoti, Bashir, Samirul, Singh, Laishram Rajendrakumar, Shah, Naveed Nazir, Fazili, Khalid Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237413/
https://www.ncbi.nlm.nih.gov/pubmed/32427833
http://dx.doi.org/10.1038/s41598-020-64860-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237413/
https://www.ncbi.nlm.nih.gov/pubmed/32427833
http://dx.doi.org/10.1038/s41598-020-64860-1

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