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Aggregation of M3 (E376D) variant of alpha1- antitrypsin
Alpha1-antitrypsin (α1AT) is an abundant serine-protease inhibitor in circulation. It has an important role in neutralizing the neutrophil elastase activity. Different pathogenic point mutations like Z((E342K))-α1AT have been implicated in the development of liver cirrhosis and Chronic Obstructive P...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237413/ https://www.ncbi.nlm.nih.gov/pubmed/32427833 http://dx.doi.org/10.1038/s41598-020-64860-1 |