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Exosomal miR-21 promotes proliferation, invasion and therapy resistance of colon adenocarcinoma cells through its target PDCD4

Exosomes contain cell-specific collections of bioactive materials including proteins, lipids, and RNAs that are transported to recipient cells to exert their impacts. MicroRNAs (miRNAs) can function as tumor suppressor or oncogenic genes and miR-21 is one of the most frequently up-regulated miRNAs i...

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Detalles Bibliográficos
Autores principales: Sun, Li-Hua, Tian, Dan, Yang, Ze-Cheng, Li, Jin-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237414/
https://www.ncbi.nlm.nih.gov/pubmed/32427870
http://dx.doi.org/10.1038/s41598-020-65207-6