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Drp1-dependent remodeling of mitochondrial morphology triggered by EBV-LMP1 increases cisplatin resistance

Latent membrane protein 1 (LMP1) is a major Epstein–Barr virus (EBV)-encoded oncoprotein involved in latency infection that regulates mitochondrial functions to facilitate cell survival. Recently, mitochondrial fission has been demonstrated as a crucial mechanism in oncovirus-mediated carcinogenesis...

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Detalles Bibliográficos
Autores principales: Xie, Longlong, Shi, Feng, Li, Yueshuo, Li, We, Yu, Xinfang, Zhao, Lin, Zhou, Min, Hu, Jianmin, Luo, Xiangjian, Tang, Min, Fan, Jia, Zhou, Jian, Gao, Qiang, Wu, Weizhong, Zhang, Xin, Liao, Weihua, Bode, Ann M., Cao, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237430/
https://www.ncbi.nlm.nih.gov/pubmed/32433544
http://dx.doi.org/10.1038/s41392-020-0151-9