Drosophila taste neurons as an agonist-screening platform for P2X receptors

The P2X receptor family of ATP-gated cation channels are attractive drug targets for pain and inflammatory disease, but no subtype-selective agonists, and few partially selective agonists have been described to date. As proof-of-concept for the discovery of novel P2X receptor agonists, here we demon...

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Detalles Bibliográficos
Autores principales: Grimes, Leanne, Griffiths, Julia, Pasqualetto, Gaia, Brancale, Andrea, Kemp, Paul J., Young, Mark T., van der Goes van Naters, Wynand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237442/
https://www.ncbi.nlm.nih.gov/pubmed/32427920
http://dx.doi.org/10.1038/s41598-020-65169-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237442/
https://www.ncbi.nlm.nih.gov/pubmed/32427920
http://dx.doi.org/10.1038/s41598-020-65169-9

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