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Drosophila taste neurons as an agonist-screening platform for P2X receptors
The P2X receptor family of ATP-gated cation channels are attractive drug targets for pain and inflammatory disease, but no subtype-selective agonists, and few partially selective agonists have been described to date. As proof-of-concept for the discovery of novel P2X receptor agonists, here we demon...
Autores principales: | Grimes, Leanne, Griffiths, Julia, Pasqualetto, Gaia, Brancale, Andrea, Kemp, Paul J., Young, Mark T., van der Goes van Naters, Wynand |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237442/ https://www.ncbi.nlm.nih.gov/pubmed/32427920 http://dx.doi.org/10.1038/s41598-020-65169-9 |
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