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Cells grown in three-dimensional spheroids mirror in vivo metabolic response of epithelial cells

Metabolism in cells adapts quickly to changes in nutrient availability and cellular differentiation status, including growth conditions in cell culture settings. The last decade saw a vast increase in three-dimensional (3D) cell culture techniques, engendering spheroids and organoids. These methods...

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Detalles Bibliográficos
Autores principales: Lagies, Simon, Schlimpert, Manuel, Neumann, Simon, Wäldin, Astrid, Kammerer, Bernd, Borner, Christoph, Peintner, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237469/
https://www.ncbi.nlm.nih.gov/pubmed/32427948
http://dx.doi.org/10.1038/s42003-020-0973-6