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SH3RF3 promotes breast cancer stem-like properties via JNK activation and PTX3 upregulation

Cancer stem-like cells (CSCs) are the tumorigenic cell subpopulation and contribute to cancer recurrence and metastasis. However, the understanding of CSC regulatory mechanisms remains incomplete. By transcriptomic analysis, we identify a scaffold protein SH3RF3 (also named POSH2) that is upregulate...

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Detalles Bibliográficos
Autores principales: Zhang, Peiyuan, Liu, Yingjie, Lian, Cheng, Cao, Xuan, Wang, Yuan, Li, Xiaoxun, Cong, Min, Tian, Pu, Zhang, Xue, Wei, Gang, Liu, Tong, Hu, Guohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237486/
https://www.ncbi.nlm.nih.gov/pubmed/32427938
http://dx.doi.org/10.1038/s41467-020-16051-9