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Mitochondrial sphingosine-1-phosphate lyase is essential for phosphatidylethanolamine synthesis and survival of Trypanosoma brucei

Sphingosine-1-phosphate is a signaling molecule involved in the control of cell migration, differentiation, survival and other physiological processes. This sphingolipid metabolite can be degraded by the action of sphingosine-1-phosphate lyase (SPL) to form hexadecenal and ethanolamine phosphate. Th...

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Detalles Bibliográficos
Autores principales: Dawoody Nejad, Ladan, Stumpe, Michael, Rauch, Monika, Hemphill, Andrew, Schneiter, Roger, Bütikofer, Peter, Serricchio, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237492/
https://www.ncbi.nlm.nih.gov/pubmed/32427974
http://dx.doi.org/10.1038/s41598-020-65248-x