Cargando…

Mitochondrial sphingosine-1-phosphate lyase is essential for phosphatidylethanolamine synthesis and survival of Trypanosoma brucei

Sphingosine-1-phosphate is a signaling molecule involved in the control of cell migration, differentiation, survival and other physiological processes. This sphingolipid metabolite can be degraded by the action of sphingosine-1-phosphate lyase (SPL) to form hexadecenal and ethanolamine phosphate. Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dawoody Nejad, Ladan, Stumpe, Michael, Rauch, Monika, Hemphill, Andrew, Schneiter, Roger, Bütikofer, Peter, Serricchio, Mauro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237492/ https://www.ncbi.nlm.nih.gov/pubmed/32427974 http://dx.doi.org/10.1038/s41598-020-65248-x

Ejemplares similares

Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei
por: Farine, Luce, et al.
Publicado: (2015)

SGPL1 (sphingosine phosphate lyase 1) modulates neuronal autophagy via phosphatidylethanolamine production
por: Mitroi, Daniel N., et al.
Publicado: (2017)

Major Surface Glycoproteins of Insect Forms of Trypanosoma brucei Are Not Essential for Cyclical Transmission by Tsetse
por: Vassella, Erik, et al.
Publicado: (2009)

Cellular and Molecular Targets of Nucleotide-Tagged Trithiolato-Bridged Arene Ruthenium Complexes in the Protozoan Parasites Toxoplasma gondii and Trypanosoma brucei
por: Anghel, Nicoleta, et al.
Publicado: (2021)

Evaluation of In Vitro Activity of Essential Oils against Trypanosoma brucei brucei and Trypanosoma evansi
por: Habila, Nathan, et al.
Publicado: (2010)

Arginine and Lysine Transporters Are Essential for Trypanosoma brucei
por: Mathieu, Christoph, et al.
Publicado: (2017)

Neurological Consequences of Sphingosine Phosphate Lyase Insufficiency
por: Atreya, Krishan B., et al.
Publicado: (2022)

The endoplasmic reticulum membrane protein complex localizes to the mitochondrial - endoplasmic reticulum interface and its subunits modulate phospholipid biosynthesis in Trypanosoma brucei
por: Iyer, Advaitha, et al.
Publicado: (2022)

Ethanolamine phosphoglycerol attachment to eEF1A is not essential for normal growth of Trypanosoma brucei
por: Greganova, Eva, et al.
Publicado: (2012)

Recent Insight into the Role of Sphingosine-1-Phosphate Lyase in Neurodegeneration
por: Wieczorek, Iga, et al.
Publicado: (2023)

Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer’s disease
por: Ceccom, Johnatan, et al.
Publicado: (2014)

An Essential Farnesylated Kinesin in Trypanosoma brucei
por: Engelson, Erin J., et al.
Publicado: (2011)

Dendritic cell sphingosine-1-phosphate lyase regulates thymic egress
por: Zamora-Pineda, Jesus, et al.
Publicado: (2016)

Deficiency of sphingosine-1-phosphate receptor 3 does not affect the skeletal phenotype of mice lacking sphingosine-1-phosphate lyase
por: Heckt, Timo, et al.
Publicado: (2019)

Autophagy in Trypanosoma brucei: Amino Acid Requirement and Regulation during Different Growth Phases
por: Schmidt, Remo S., et al.
Publicado: (2014)

Proline Metabolism is Essential for Trypanosoma brucei brucei Survival in the Tsetse Vector
por: Mantilla, Brian S., et al.
Publicado: (2017)

Acquired modification of sphingosine-1-phosphate lyase activity is not related to adrenal insufficiency
por: Sunter, Gulin, et al.
Publicado: (2018)

Sphingolipids in Ventilator Induced Lung Injury: Role of Sphingosine-1-Phosphate Lyase
por: Suryadevara, Vidyani, et al.
Publicado: (2018)

Sphingosine-1-phosphate lyase (SGPL1) deficiency is associated with mitochondrial dysfunction
por: Maharaj, A., et al.
Publicado: (2020)

Sphingosine-1 Phosphate Lyase Regulates Sensitivity of Pancreatic Beta-Cells to Lipotoxicity
por: Tang, Yadi, et al.
Publicado: (2021)

Sphingosine 1-Phosphate Lyase in the Developing and Injured Nervous System: a Dichotomy?
por: Xiao, Junhua
Publicado: (2023)

Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer
por: Matula, Kasia, et al.
Publicado: (2015)

Vitamin B6 prevents excessive inflammation by reducing accumulation of sphingosine‐1‐phosphate in a sphingosine‐1‐phosphate lyase–dependent manner
por: Du, Xialin, et al.
Publicado: (2020)

A Conserved Mitochondrial Chaperone-Protease Complex Involved in Protein Homeostasis
por: Serricchio, Mauro, et al.
Publicado: (2021)

Partial Deficiency of Sphingosine-1-Phosphate Lyase Confers Protection in Experimental Autoimmune Encephalomyelitis
por: Billich, Andreas, et al.
Publicado: (2013)

Characterization of homologous sphingosine-1-phosphate lyase isoforms in the bacterial pathogen Burkholderia pseudomallei
por: McLean, Christopher J., et al.
Publicado: (2017)

Sphingosine 1- Phosphate Lyase Insufficiency Syndrome (SPLIS); A Role in Multiple Endocrinopathies
por: Wai Kwong, Ruth Ming, et al.
Publicado: (2021)

Sphingosine 1‐phosphate lyase facilitates cancer progression through converting sphingolipids to glycerophospholipids
por: Uranbileg, Baasanjav, et al.
Publicado: (2022)

An Atypical Mitochondrial Carrier That Mediates Drug Action in Trypanosoma brucei
por: de Macêdo, Juan P., et al.
Publicado: (2015)

Persistence of Trypanosoma brucei as early procyclic forms and social motility are dependent on glycosylphosphatidylinositol transamidase
por: Knüsel, Sebastian, et al.
Publicado: (2022)

Handling Uncertainty in Dynamic Models: The Pentose Phosphate Pathway in Trypanosoma brucei
por: Kerkhoven, Eduard J., et al.
Publicado: (2013)

Sphingosine-1-Phosphate Lyase Deficient Cells as a Tool to Study Protein Lipid Interactions
por: Gerl, Mathias J., et al.
Publicado: (2016)

The Sphingosine-1-Phosphate Lyase (LegS2) Contributes to the Restriction of Legionella pneumophila in Murine Macrophages
por: Abu Khweek, Arwa, et al.
Publicado: (2016)

Suppression of sphingosine 1-phosphate lyase retards the liver regeneration in mice after partial hepatectomy
por: Kageyama, Yuko, et al.
Publicado: (2020)

A Sphingosine-1-Phosphate Lyase Mutation Associated With Congenital Nephrotic Syndrome and Multiple Endocrinopathy
por: Maharaj, Avinaash, et al.
Publicado: (2020)

Sphingosine‐1‐phosphate‐lyase deficiency affects glucose metabolism in a way that abets oncogenesis
por: Afsar, Sumaiya Y., et al.
Publicado: (2022)

A Structural Domain Mediates Attachment of Ethanolamine Phosphoglycerol to Eukaryotic Elongation Factor 1A in Trypanosoma brucei
por: Greganova, Eva, et al.
Publicado: (2010)

Pyrimidine Biosynthesis Is Not an Essential Function for Trypanosoma brucei Bloodstream Forms
por: Ali, Juma A. M., et al.
Publicado: (2013)

SUMOylation in Trypanosoma brucei
por: Klein, Cornelia Andrea, et al.
Publicado: (2013)

Trypanosoma evansi is alike to Trypanosoma brucei brucei in the subcellular localisation of glycolytic enzymes
por: Moreno, S Andrea, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_p8r30ov6uvhcf54e3puf234qrj