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Strategies to Obtain Encapsulation and Controlled Release of Small Hydrophilic Molecules
The therapeutic effect of small hydrophilic molecules is limited by the rapid clearance from the systemic circulation or a local site of administration. The unsuitable pharmacokinetics and biodistribution can be improved by encapsulating them in drug delivery systems. However, the high-water solubil...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237580/ https://www.ncbi.nlm.nih.gov/pubmed/32478055 http://dx.doi.org/10.3389/fbioe.2020.00437 |