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From GWAS to Function: Using Functional Genomics to Identify the Mechanisms Underlying Complex Diseases

Genome-wide association studies (GWAS) have successfully mapped thousands of loci associated with complex traits. These associations could reveal the molecular mechanisms altered in common complex diseases and result in the identification of novel drug targets. However, GWAS have also left a number...

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Detalles Bibliográficos
Autores principales: Cano-Gamez, Eddie, Trynka, Gosia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237642/
https://www.ncbi.nlm.nih.gov/pubmed/32477401
http://dx.doi.org/10.3389/fgene.2020.00424