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Tau affects P53 function and cell fate during the DNA damage response

Cells are constantly exposed to DNA damaging insults. To protect the organism, cells developed a complex molecular response coordinated by P53, the master regulator of DNA repair, cell division and cell fate. DNA damage accumulation and abnormal cell fate decision may represent a pathomechanism shar...

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Detalles Bibliográficos
Autores principales: Sola, Martina, Magrin, Claudia, Pedrioli, Giona, Pinton, Sandra, Salvadè, Agnese, Papin, Stéphanie, Paganetti, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237658/
https://www.ncbi.nlm.nih.gov/pubmed/32427887
http://dx.doi.org/10.1038/s42003-020-0975-4