Cargando…
Tau affects P53 function and cell fate during the DNA damage response
Cells are constantly exposed to DNA damaging insults. To protect the organism, cells developed a complex molecular response coordinated by P53, the master regulator of DNA repair, cell division and cell fate. DNA damage accumulation and abnormal cell fate decision may represent a pathomechanism shar...
Autores principales: | Sola, Martina, Magrin, Claudia, Pedrioli, Giona, Pinton, Sandra, Salvadè, Agnese, Papin, Stéphanie, Paganetti, Paolo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237658/ https://www.ncbi.nlm.nih.gov/pubmed/32427887 http://dx.doi.org/10.1038/s42003-020-0975-4 |
Ejemplares similares
-
Split GFP technologies to structurally characterize and quantify functional biomolecular interactions of FTD-related proteins
por: Foglieni, Chiara, et al.
Publicado: (2017) -
Phosphorylation of nuclear Tau is modulated by distinct cellular pathways
por: Ulrich, Giorgio, et al.
Publicado: (2018) -
Tau protein binds to the P53 E3 ubiquitin ligase MDM2
por: Sola, Martina, et al.
Publicado: (2023) -
Tau accumulation in degradative organelles is associated to lysosomal stress
por: Piovesana, Ester, et al.
Publicado: (2023) -
Cancer-specific association between Tau (MAPT) and cellular pathways, clinical outcome, and drug response
por: Callari, Maurizio, et al.
Publicado: (2023)