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Thymic resident NKT cell subsets show differential requirements for CD28 co-stimulation during antigenic activation

Natural killer T (NKT) cells rapidly respond to antigenic stimulation with cytokine production and direct cytotoxicity. These innate-like characteristics arise from their differentiation into mature effector cells during thymic development. A subset of mature NKT cells remain thymic resident, but th...

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Detalles Bibliográficos
Autores principales: Shissler, Susannah C., Singh, Nevil J., Webb, Tonya J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237672/
https://www.ncbi.nlm.nih.gov/pubmed/32427927
http://dx.doi.org/10.1038/s41598-020-65129-3