Cargando…
Thymic resident NKT cell subsets show differential requirements for CD28 co-stimulation during antigenic activation
Natural killer T (NKT) cells rapidly respond to antigenic stimulation with cytokine production and direct cytotoxicity. These innate-like characteristics arise from their differentiation into mature effector cells during thymic development. A subset of mature NKT cells remain thymic resident, but th...
Autores principales: | Shissler, Susannah C., Singh, Nevil J., Webb, Tonya J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237672/ https://www.ncbi.nlm.nih.gov/pubmed/32427927 http://dx.doi.org/10.1038/s41598-020-65129-3 |
Ejemplares similares
-
Mixed Signals: Co-Stimulation in Invariant Natural Killer T Cell-Mediated Cancer Immunotherapy
por: Shissler, Susannah C., et al.
Publicado: (2017) -
Novel lipid antigens for NKT cells in cancer
por: Lee, Michael S., et al.
Publicado: (2023) -
Antigen-presenting T cells provide critical B7 co-stimulation for thymic iNKT cell development via CD28-dependent trogocytosis
por: Watanabe, Masashi, et al.
Publicado: (2022) -
TCR signal strength controls thymic differentiation of iNKT cell subsets
por: Tuttle, Kathryn D., et al.
Publicado: (2018) -
The Timing and Abundance of IL-2Rβ (CD122) Expression Control Thymic iNKT Cell Generation and NKT1 Subset Differentiation
por: Won, Hee Yeun, et al.
Publicado: (2021)