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Repurposed Analog of GLP-1 Ameliorates Hyperglycemia in Type 1 Diabetic Mice Through Pancreatic Cell Reprogramming

Type 1 diabetes is an autoimmune disease caused by the destruction of the insulin-producing β-cells. An ideal immunotherapy should combine the blockade of the autoimmune response with the recovery of functional target cell mass. With the aim to develop new therapies for type 1 diabetes that could co...

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Detalles Bibliográficos
Autores principales: Villalba, Adrian, Rodriguez-Fernandez, Silvia, Perna-Barrull, David, Ampudia, Rosa-Maria, Gomez-Muñoz, Laia, Pujol-Autonell, Irma, Aguilera, Eva, Coma, Mireia, Cano-Sarabia, Mary, Vázquez, Federico, Verdaguer, Joan, Vives-Pi, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237704/
https://www.ncbi.nlm.nih.gov/pubmed/32477262
http://dx.doi.org/10.3389/fendo.2020.00258