Thanatin Impairs Lipopolysaccharide Transport Complex Assembly by Targeting LptC–LptA Interaction and Decreasing LptA Stability

The outer membrane (OM) of Gram-negative bacteria is a highly selective permeability barrier due to its asymmetric structure with lipopolysaccharide (LPS) in the outer leaflet. In Escherichia coli, LPS is transported to the cell surface by the LPS transport (Lpt) system composed of seven essential p...

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Detalles Bibliográficos
Autores principales: Moura, Elisabete C. C. M., Baeta, Tiago, Romanelli, Alessandra, Laguri, Cedric, Martorana, Alessandra M., Erba, Emanuela, Simorre, Jean-Pierre, Sperandeo, Paola, Polissi, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237710/
https://www.ncbi.nlm.nih.gov/pubmed/32477309
http://dx.doi.org/10.3389/fmicb.2020.00909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237710/
https://www.ncbi.nlm.nih.gov/pubmed/32477309
http://dx.doi.org/10.3389/fmicb.2020.00909

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