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Accelerating fragment-based library generation by coupling high-performance photoreactors with benchtop analysis

Herein we report a workflow coupling photoredox-nickel dual-catalyzed N-arylation reactions to benchtop analysis for the efficient generation of fragment-based libraries. Technological advances in photoreactor design facilitated reliable and reproducible experimentation. Knowledge on the reactivity...

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Detalles Bibliográficos
Autores principales: Lefebvre, Quentin, Salomé, Christophe, Fessard, Thomas C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237803/
https://www.ncbi.nlm.nih.gov/pubmed/32509029
http://dx.doi.org/10.3762/bjoc.16.87