Identification of genomic enhancers through spatial integration of single‐cell transcriptomics and epigenomics

Single‐cell technologies allow measuring chromatin accessibility and gene expression in each cell, but jointly utilizing both layers to map bona fide gene regulatory networks and enhancers remains challenging. Here, we generate independent single‐cell RNA‐seq and single‐cell ATAC‐seq atlases of the...

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Detalles Bibliográficos
Autores principales: Bravo González‐Blas, Carmen, Quan, Xiao‐Jiang, Duran‐Romaña, Ramon, Taskiran, Ibrahim Ihsan, Koldere, Duygu, Davie, Kristofer, Christiaens, Valerie, Makhzami, Samira, Hulselmans, Gert, de Waegeneer, Maxime, Mauduit, David, Poovathingal, Suresh, Aibar, Sara, Aerts, Stein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237818/
https://www.ncbi.nlm.nih.gov/pubmed/32431014
http://dx.doi.org/10.15252/msb.20209438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237818/
https://www.ncbi.nlm.nih.gov/pubmed/32431014
http://dx.doi.org/10.15252/msb.20209438

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