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ESC‐sEVs Rejuvenate Senescent Hippocampal NSCs by Activating Lysosomes to Improve Cognitive Dysfunction in Vascular Dementia

Vascular dementia (VD) is one of the most common types of dementia, however, the intrinsic mechanism is unclear and there is still lack of effective medications. In this study, the VD rats exhibit a progressive cognitive impairment, as well as a time‐related increasing in hippocampal neural stem cel...

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Detalles Bibliográficos
Autores principales: Hu, Guowen, Xia, Yuguo, Zhang, Juntao, Chen, Yu, Yuan, Ji, Niu, Xin, Zhao, Bizeng, Li, Qing, Wang, Yang, Deng, Zhifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237844/
https://www.ncbi.nlm.nih.gov/pubmed/32440476
http://dx.doi.org/10.1002/advs.201903330