Cargando…

ESC‐sEVs Rejuvenate Senescent Hippocampal NSCs by Activating Lysosomes to Improve Cognitive Dysfunction in Vascular Dementia

Vascular dementia (VD) is one of the most common types of dementia, however, the intrinsic mechanism is unclear and there is still lack of effective medications. In this study, the VD rats exhibit a progressive cognitive impairment, as well as a time‐related increasing in hippocampal neural stem cel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Guowen, Xia, Yuguo, Zhang, Juntao, Chen, Yu, Yuan, Ji, Niu, Xin, Zhao, Bizeng, Li, Qing, Wang, Yang, Deng, Zhifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237844/ https://www.ncbi.nlm.nih.gov/pubmed/32440476 http://dx.doi.org/10.1002/advs.201903330

Ejemplares similares

Human ESC-sEVs alleviate age-related bone loss by rejuvenating senescent bone marrow-derived mesenchymal stem cells
por: Gong, Liangzhi, et al.
Publicado: (2020)

iPSC-sEVs alleviate microglia senescence to protect against ischemic stroke in aged mice
por: Niu, Xinyu, et al.
Publicado: (2023)

Detection of Inflammation-Related Melanoma Small Extracellular Vesicle (sEV) mRNA Content Using Primary Melanocyte sEVs as a Reference
por: Bardi, Gina T., et al.
Publicado: (2019)

Signaling of Tumor-Derived sEV Impacts Melanoma Progression
por: Zebrowska, Aneta, et al.
Publicado: (2020)

Rab13 regulates sEV secretion in mutant KRAS colorectal cancer cells
por: Hinger, Scott A., et al.
Publicado: (2020)

Effects of sEV derived from SHED and DPSC on the proliferation, migration and osteogenesis of PDLSC
por: Zheng, Yexin, et al.
Publicado: (2023)

Regenerative and protective effects of dMSC-sEVs on high-glucose-induced senescent fibroblasts by suppressing RAGE pathway and activating Smad pathway
por: Bian, Xiaowei, et al.
Publicado: (2020)

Proof of concept of using a membrane-sensing peptide for sEVs affinity-based isolation
por: Benayas, Beatriz, et al.
Publicado: (2023)

Small extracellular vesicles secreted by human iPSC-derived MSC enhance angiogenesis through inhibiting STAT3-dependent autophagy in ischemic stroke
por: Xia, Yuguo, et al.
Publicado: (2020)

Human embryonic stem cell-derived exosomes promote pressure ulcer healing in aged mice by rejuvenating senescent endothelial cells
por: Chen, Bi, et al.
Publicado: (2019)

A Role for mir-26a in Stress: A Potential sEV Biomarker and Modulator of Excitatory Neurotransmission
por: Lafourcade, Carlos Andrés, et al.
Publicado: (2020)

Assessment of Tumorigenic Potential in Mesenchymal-Stem/Stromal-Cell-Derived Small Extracellular Vesicles (MSC-sEV)
por: Tan, Thong Teck, et al.
Publicado: (2021)

Phosphatidylserine-deficient small extracellular vesicle is a major somatic cell-derived sEV subpopulation in blood
por: Matsumoto, Akihiro, et al.
Publicado: (2021)

Neurotransmitter-stimulated neuron-derived sEVs have opposite effects on amyloid β-induced neuronal damage
por: Dou, Yunxiao, et al.
Publicado: (2021)

Small Extracellular Vesicles (sEVs) Biogenesis Molecular Players Are Associated with Clinical Outcome of Colorectal Cancer Patients
por: Kottorou, Anastasia, et al.
Publicado: (2023)

3D ECM-Based Scaffolds Boost Young Cell Secretome-Derived EV Rejuvenating Effects in Senescent Cells
por: Arcuri, Sharon, et al.
Publicado: (2023)

Semipermeable Cellulose Beads Allow Selective and Continuous Release of Small Extracellular Vesicles (sEV) From Encapsulated Cells
por: Zavala, Gabriela, et al.
Publicado: (2020)

αvβ3-targeted sEVs for efficient intracellular delivery of proteins using MFG-E8
por: Mai, Junxin, et al.
Publicado: (2022)

Neutrophil membrane engineered HucMSC sEVs alleviate cisplatin-induced AKI by enhancing cellular uptake and targeting
por: Wu, Peipei, et al.
Publicado: (2022)

SERS spectroscopy with machine learning to analyze human plasma derived sEVs for coronary artery disease diagnosis and prognosis
por: Huang, Xi, et al.
Publicado: (2022)

Hypoxic culture of umbilical cord mesenchymal stem cell-derived sEVs prompts peripheral nerve injury repair
por: Zhu, Ziying, et al.
Publicado: (2023)

MSC−sEV Treatment Polarizes Pro−Fibrotic M2 Macrophages without Exacerbating Liver Fibrosis in NASH
por: Zhang, Bin, et al.
Publicado: (2023)

A simple and available measurement of onco-sEV dsDNA to protein ratio as a potential tumor marker
por: Sun, Yifan, et al.
Publicado: (2023)

SEV (Version 1 1) User's Guide (SEV is a tool to select events)
por: Strizzolo, C
Publicado: (1991)

Neural Stem Cells (NSCs) and Proteomics
por: Shoemaker, Lorelei D., et al.
Publicado: (2016)

Renal cancer stem cell-derived sEVs impair renal function by inducing renal cell ERS and apoptosis in mice
por: Wu, Ruoyu, et al.
Publicado: (2022)

Gold Nanopyramid Arrays for Non-Invasive Surface-Enhanced Raman Spectroscopy-Based Gastric Cancer Detection via sEVs
por: Liu, Zirui, et al.
Publicado: (2022)

Human amniotic epithelial cells exert anti-cancer effects through secretion of immunomodulatory small extracellular vesicles (sEV)
por: Bolouri, Mohammad-Reza, et al.
Publicado: (2022)

BM-MSC-derived small extracellular vesicles (sEV) from trained animals presented nephroprotective potential in unilateralureteral obstruction model
por: Luiz, Rafael da Silva, et al.
Publicado: (2021)

CA-IX-Expressing Small Extracellular Vesicles (sEVs) Are Released by Melanoma Cells under Hypoxia and in the Blood of Advanced Melanoma Patients
por: Venturella, Marta, et al.
Publicado: (2023)

A sensitive and rapid electrochemical biosensor for sEV-miRNA detection based on domino-type localized catalytic hairpin assembly
por: Li, Wenbin, et al.
Publicado: (2023)

Cellular senescence, rejuvenation and potential immortality
por: Sheldrake, A. Rupert
Publicado: (2022)

Inflammatory stimulation of astrocytes affects the expression of miRNA-22-3p within NSCs-EVs regulating remyelination by targeting KDM3A
por: Han, Tianyu, et al.
Publicado: (2023)

Embryonic Stem Cells‐Derived Exosomes Endowed with Targeting Properties as Chemotherapeutics Delivery Vehicles for Glioblastoma Therapy
por: Zhu, Qingwei, et al.
Publicado: (2019)

Bone Mesenchymal Stem Cell-Derived sEV-Encapsulated Thermosensitive Hydrogels Accelerate Osteogenesis and Angiogenesis by Release of Exosomal miR-21
por: Wu, Di, et al.
Publicado: (2022)

hucMSC-sEVs-Derived 14-3-3ζ Serves as a Bridge between YAP and Autophagy in Diabetic Kidney Disease
por: Yin, Siqi, et al.
Publicado: (2022)

Protein Biomarker Discovery Studies on Urinary sEV Fractions Separated with UF-SEC for the First Diagnosis and Detection of Recurrence in Bladder Cancer Patients
por: Jordaens, Stephanie, et al.
Publicado: (2023)

M2 Macrophage‐Derived sEV Regulate Pro‐Inflammatory CCR2(+) Macrophage Subpopulations to Favor Post‐AMI Cardiac Repair
por: Li, Lan, et al.
Publicado: (2023)

Mesenchymal Stem/Stromal Cell-Derived Small Extracellular Vesicles (MSC-sEVs): A Promising Treatment Modality for Diabetic Foot Ulcer
por: Kouroupis, Dimitrios, et al.
Publicado: (2023)

Editorial: Mesenchymal Stem Cell Senescence and Rejuvenation
por: Zhang, Yuelin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ibacco4jjbvmc5u9iono5nqn6a