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MorphoSeq: Full Single-Cell Transcriptome Dynamics Up to Gastrulation in a Chordate

Single-cell RNA sequencing (scRNA-seq) provides a leap forward in resolving cellular diversity and developmental trajectories but fails to comprehensively delineate the spatial organization and precise cellular makeup of individual embryos. Here, we reconstruct from scRNA-seq and light sheet imaging...

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Detalles Bibliográficos
Autores principales: Sladitschek, Hanna L., Fiuza, Ulla-Maj, Pavlinic, Dinko, Benes, Vladimir, Hufnagel, Lars, Neveu, Pierre A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237864/
https://www.ncbi.nlm.nih.gov/pubmed/32315617
http://dx.doi.org/10.1016/j.cell.2020.03.055