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Genomics of Blood Pressure and Hypertension: Extending the Mosaic Theory Toward Stratification

The genetic architecture of blood pressure (BP) now includes more than 30 genes, with rare mutations resulting in inherited forms of hypertension or hypotension, and 1477 common single-nucleotide polymorphisms (SNPs). These signify the heterogeneity of the BP phenotype and support the mosaic theory...

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Detalles Bibliográficos
Autores principales: Lip, Stefanie, Padmanabhan, Sandosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pulsus Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237883/
https://www.ncbi.nlm.nih.gov/pubmed/32389342
http://dx.doi.org/10.1016/j.cjca.2020.03.001