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Genomics of Blood Pressure and Hypertension: Extending the Mosaic Theory Toward Stratification
The genetic architecture of blood pressure (BP) now includes more than 30 genes, with rare mutations resulting in inherited forms of hypertension or hypotension, and 1477 common single-nucleotide polymorphisms (SNPs). These signify the heterogeneity of the BP phenotype and support the mosaic theory...
Autores principales: | Lip, Stefanie, Padmanabhan, Sandosh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pulsus Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237883/ https://www.ncbi.nlm.nih.gov/pubmed/32389342 http://dx.doi.org/10.1016/j.cjca.2020.03.001 |
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