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Interleukin-33 Signaling Controls the Development of Iron-Recycling Macrophages

Splenic red pulp macrophages (RPMs) contribute to erythrocyte homeostasis and are required for iron recycling. Heme induces the expression of SPIC transcription factor in monocyte-derived macrophages and promotes their differentiation into RPM precursors, pre-RPMs. However, the requirements for diff...

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Detalles Bibliográficos
Autores principales: Lu, Yuning, Basatemur, Gemma, Scott, Ian C., Chiarugi, Davide, Clement, Marc, Harrison, James, Jugdaohsingh, Ravin, Yu, Xian, Newland, Stephen A., Jolin, Helen E., Li, Xuan, Chen, Xiao, Szymanska, Monika, Haraldsen, Guttorm, Palmer, Gaby, Fallon, Padraic G., Cohen, E. Suzanne, McKenzie, Andrew N.J., Mallat, Ziad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237885/
https://www.ncbi.nlm.nih.gov/pubmed/32272082
http://dx.doi.org/10.1016/j.immuni.2020.03.006