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Interleukin-33 Signaling Controls the Development of Iron-Recycling Macrophages
Splenic red pulp macrophages (RPMs) contribute to erythrocyte homeostasis and are required for iron recycling. Heme induces the expression of SPIC transcription factor in monocyte-derived macrophages and promotes their differentiation into RPM precursors, pre-RPMs. However, the requirements for diff...
Autores principales: | Lu, Yuning, Basatemur, Gemma, Scott, Ian C., Chiarugi, Davide, Clement, Marc, Harrison, James, Jugdaohsingh, Ravin, Yu, Xian, Newland, Stephen A., Jolin, Helen E., Li, Xuan, Chen, Xiao, Szymanska, Monika, Haraldsen, Guttorm, Palmer, Gaby, Fallon, Padraic G., Cohen, E. Suzanne, McKenzie, Andrew N.J., Mallat, Ziad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237885/ https://www.ncbi.nlm.nih.gov/pubmed/32272082 http://dx.doi.org/10.1016/j.immuni.2020.03.006 |
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