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Anticrystal Engineering of Ketoprofen and Ester Local Anesthetics: Ionic Liquids or Deep Eutectic Mixtures?

Ionic liquids (ILs) and deep eutectic mixtures (DEMs) are potential solutions to the problems of low solubility, polymorphism, and low bioavailability of drugs. The aim of this work was to develop and investigate ketoprofen (KET)-based ILs/DEMs containing an ester local anesthetic (LA): benzocaine (...

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Detalles Bibliográficos
Autores principales: Umerska, Anita, Bialek, Klaudia, Zotova, Julija, Skotnicki, Marcin, Tajber, Lidia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237996/
https://www.ncbi.nlm.nih.gov/pubmed/32316479
http://dx.doi.org/10.3390/pharmaceutics12040368