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Influence of Carbamazepine Dihydrate on the Preparation of Amorphous Solid Dispersions by Hot Melt Extrusion

Amorphous solid dispersions (ASDs) are commonly used in the pharmaceutical industry to improve the dissolution and bioavailability of poorly water-soluble drugs. Hot melt extrusion (HME) has been employed to prepare ASD based products. However, due to the narrow processing window of HME, ASDs are no...

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Detalles Bibliográficos
Autores principales: Ma, Xiangyu, Müller, Felix, Huang, Siyuan, Lowinger, Michael, Liu, Xu, Schooler, Rebecca, Williams, Robert O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238004/
https://www.ncbi.nlm.nih.gov/pubmed/32326114
http://dx.doi.org/10.3390/pharmaceutics12040379