Lipid Nanoparticle Inclusion Prevents Capsaicin-Induced TRPV1 Defunctionalization

Background: Capsaicin (CPS) is a highly selective agonist of the transient receptor potential vanilloid type 1 (TRPV1) with a nanomolar affinity. High doses or prolonged exposure to CPS induces TRPV1 defunctionalization and, although this effect is currently used for the treatment of thermal hyperal...

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Detalles Bibliográficos
Autores principales: Puglia, Carmelo, Santonocito, Debora, Bonaccorso, Angela, Musumeci, Teresa, Ruozi, Barbara, Pignatello, Rosario, Carbone, Claudia, Parenti, Carmela, Chiechio, Santina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238012/
https://www.ncbi.nlm.nih.gov/pubmed/32290081
http://dx.doi.org/10.3390/pharmaceutics12040339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238012/
https://www.ncbi.nlm.nih.gov/pubmed/32290081
http://dx.doi.org/10.3390/pharmaceutics12040339

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