Changing the Drug Delivery System: Does it Add to Non-Compliance Ramifications Control? A Simulation Study on the Pharmacokinetics and Pharmacodynamics of Atypical Antipsychotic Drug

This study investigates the pharmacokinetic (PK) and pharmacodynamic (PD) consequences of shifting from Quetiapine fumarate immediate-release (IR) to extended-release (XR) formulation in non-adherent schizophrenia patients. Monte-Carlo simulations using population PK and PD models were implemented t...

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Detalles Bibliográficos
Autor principal: Elkomy, Mohammed H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238021/
https://www.ncbi.nlm.nih.gov/pubmed/32218187
http://dx.doi.org/10.3390/pharmaceutics12040297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238021/
https://www.ncbi.nlm.nih.gov/pubmed/32218187
http://dx.doi.org/10.3390/pharmaceutics12040297

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