Spatially Resolved Effects of Protein Freeze-Thawing in a Small-Scale Model Using Monoclonal Antibodies

Protein freeze-thawing is frequently used to stabilize and store recombinantly produced proteins after different unit operations in upstream and downstream processing. However, freeze-thawing is often accompanied by product damage and, hence, loss of product. Different effects are responsible, inclu...

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Detalles Bibliográficos
Autores principales: Spadiut, Oliver, Gundinger, Thomas, Pittermann, Birgit, Slouka, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238022/
https://www.ncbi.nlm.nih.gov/pubmed/32326286
http://dx.doi.org/10.3390/pharmaceutics12040382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238022/
https://www.ncbi.nlm.nih.gov/pubmed/32326286
http://dx.doi.org/10.3390/pharmaceutics12040382

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