Pharmaceutical Characterization and In Vivo Evaluation of Orlistat Formulations Prepared by the Supercritical Melt-Adsorption Method Using Carbon Dioxide: Effects of Mesoporous Silica Type

Orlistat, an anti-obesity drug, has two critical issues—the first is its low efficacy due to low water solubility and the second is side effects such as oily spotting due to its lipase inhibition. The present study was designed to propose a solution using a formulation with mesoporous silica to simu...

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Detalles Bibliográficos
Autores principales: Park, Heejun, Cha, Kwang-Ho, Hong, Seung Hyeon, Abuzar, Sharif Md, Lee, Seungyeol, Ha, Eun-Sol, Kim, Jeong-Soo, Baek, In-Hwan, Kim, Min-Soo, Hwang, Sung-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238058/
https://www.ncbi.nlm.nih.gov/pubmed/32276311
http://dx.doi.org/10.3390/pharmaceutics12040333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238058/
https://www.ncbi.nlm.nih.gov/pubmed/32276311
http://dx.doi.org/10.3390/pharmaceutics12040333

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