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Multi-Methodological Quantitative Taste Assessment of Anti-Tuberculosis Drugs to Support the Development of Palatable Paediatric Dosage Forms

The unpalatability of antituberculosis drugs is often cited as a major cause of non-adherence in children, yet limited quantitative taste assessment data are available. The aim of this research was to quantify the bitterness of isoniazid, rifampicin, pyrazinamide, and ethambutol dihydrochloride usin...

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Detalles Bibliográficos
Autores principales: Keating, Alison V., Soto, Jessica, Forbes, Claire, Zhao, Min, Craig, Duncan Q. M., Tuleu, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238065/
https://www.ncbi.nlm.nih.gov/pubmed/32316692
http://dx.doi.org/10.3390/pharmaceutics12040369