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In-Vitro and In-Vivo Evaluation of Velpatasvir- Loaded Mesoporous Silica Scaffolds. A Prospective Carrier for Drug Bioavailability Enhancement

The limited aqueous solubility of many active pharmaceutical ingredients (APIs) is responsible for their poor performance and low drug levels in blood and at target sites. Various approaches have been adopted to tackle this issue. Most recently, mesoporous silica nanoparticles (MSN) have gained atte...

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Detalles Bibliográficos
Autores principales: Mehmood, Yasir, Khan, Ikram Ullah, Shahzad, Yasser, Khan, Rizwan Ullah, Iqbal, Muhammad Shahid, Khan, Haseeb Ahmad, Khalid, Ikrima, Yousaf, Abid Mehmood, Khalid, Syed Haroon, Asghar, Sajid, Asif, Muhammad, Hussain, Talib, Shah, Shefaat Ullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238066/
https://www.ncbi.nlm.nih.gov/pubmed/32231052
http://dx.doi.org/10.3390/pharmaceutics12040307