L-Type Amino Acid Transporter 1-Utilizing Prodrugs of Ketoprofen Can Efficiently Reduce Brain Prostaglandin Levels

In order to efficiently combat neuroinflammation, it is essential to deliver the anti-inflammatory drugs to their target sites in the brain. Pro-drugs utilizing the L-type amino acid transporter 1 (LAT1) can be transported across the blood-brain barrier (BBB) and the cellular barriers of the brain’s...

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Detalles Bibliográficos
Autores principales: Montaser, Ahmed, Lehtonen, Marko, Gynther, Mikko, Huttunen, Kristiina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238114/
https://www.ncbi.nlm.nih.gov/pubmed/32290494
http://dx.doi.org/10.3390/pharmaceutics12040344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238114/
https://www.ncbi.nlm.nih.gov/pubmed/32290494
http://dx.doi.org/10.3390/pharmaceutics12040344

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