Improved Dissolution and Pharmacokinetics of Abiraterone through KinetiSol(®) Enabled Amorphous Solid Dispersions

Abiraterone is a poorly water-soluble drug. It has a high melting point and limited solubility in organic solvents, making it difficult to formulate as an amorphous solid dispersion (ASD) with conventional technologies. KinetiSol(®) is a high-energy, fusion-based, solvent-free technology that can pr...

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Detalles Bibliográficos
Autores principales: Gala, Urvi, Miller, Dave, Williams, Robert O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238130/
https://www.ncbi.nlm.nih.gov/pubmed/32295245
http://dx.doi.org/10.3390/pharmaceutics12040357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238130/
https://www.ncbi.nlm.nih.gov/pubmed/32295245
http://dx.doi.org/10.3390/pharmaceutics12040357

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