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Improved Dissolution and Pharmacokinetics of Abiraterone through KinetiSol(®) Enabled Amorphous Solid Dispersions

Abiraterone is a poorly water-soluble drug. It has a high melting point and limited solubility in organic solvents, making it difficult to formulate as an amorphous solid dispersion (ASD) with conventional technologies. KinetiSol(®) is a high-energy, fusion-based, solvent-free technology that can pr...

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Detalles Bibliográficos
Autores principales:	Gala, Urvi, Miller, Dave, Williams, Robert O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238130/ https://www.ncbi.nlm.nih.gov/pubmed/32295245 http://dx.doi.org/10.3390/pharmaceutics12040357

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