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Efficacy of a Protein Vaccine and a Conjugate Vaccine Against Co-Colonization with Vaccine-Type and Non-Vaccine Type Pneumococci in Mice

Widespread use of pneumococcal conjugate vaccines (PCVs) has led to substitution of vaccine-type (VT) strains by non-vaccine type (NVT) strains in nasopharyngeal carriage. We compared the efficacy of PCV13 and a nasal protein formulation containing pneumococcal surface protein A (PspA) adjuvanted wi...

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Detalles Bibliográficos
Autores principales: Colichio, Gabriela B. C., Oliveira, Giuliana S., Rodrigues, Tasson C., Oliveira, Maria Leonor S., Miyaji, Eliane N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238145/
https://www.ncbi.nlm.nih.gov/pubmed/32290340
http://dx.doi.org/10.3390/pathogens9040278