Importance of Mesoporous Silica Particle Size in the Stabilization of Amorphous Pharmaceuticals—The Case of Simvastatin

In this paper, the role of mesoporous silica (MS) particle size in the stabilization of amorphous simvastatin (SVT) is revealed. For inhibiting recrystallization of the supercooled drug, the two MS materials (Syloid(®) XDP 3050 and Syloid(®) 244 FP) were employed. The crystallization tendency of SVT...

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Detalles Bibliográficos
Autores principales: Knapik-Kowalczuk, Justyna, Kramarczyk, Daniel, Chmiel, Krzysztof, Romanova, Jana, Kawakami, Kohsaku, Paluch, Marian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238159/
https://www.ncbi.nlm.nih.gov/pubmed/32331310
http://dx.doi.org/10.3390/pharmaceutics12040384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238159/
https://www.ncbi.nlm.nih.gov/pubmed/32331310
http://dx.doi.org/10.3390/pharmaceutics12040384

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