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Application of 1-Hydroxy-4,5-Dimethyl-Imidazole 3-Oxide as Coformer in Formation of Pharmaceutical Cocrystals

Two, well defined binary crystals with 1-Hydroxy-4,5-Dimethyl-Imidazole 3-Oxide (HIMO) as coformer and thiobarbituric acid (TBA) as well barbituric acid (BA) as Active Pharmaceutical Ingredients (APIs) were obtained by cocrystallization (from methanol) or mechanochemically by grinding. The progress...

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Detalles Bibliográficos
Autores principales: Wróblewska, Aneta, Śniechowska, Justyna, Kaźmierski, Sławomir, Wielgus, Ewelina, Bujacz, Grzegorz D., Mlostoń, Grzegorz, Chworos, Arkadiusz, Suwara, Justyna, Potrzebowski, Marek J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238160/
https://www.ncbi.nlm.nih.gov/pubmed/32326428
http://dx.doi.org/10.3390/pharmaceutics12040359