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Phenformin Attenuates Renal Injury in Unilateral Ureteral Obstructed Mice without Affecting Immune Cell Infiltration

Phenformin and metformin are antihyperglycemic drugs that belong to the class of biguanides. Previously, we demonstrated that metformin elicits renoprotective effects in unilateral ureteral obstructed mice by reducing the infiltration of immune cells into the kidney. Since phenformin is a more poten...

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Detalles Bibliográficos
Autores principales: Nørgård, Mikkel Ø., Christensen, Michael, Mutsaers, Henricus A.M., Nørregaard, Rikke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238166/
https://www.ncbi.nlm.nih.gov/pubmed/32224876
http://dx.doi.org/10.3390/pharmaceutics12040301