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Senescence of IPF Lung Fibroblasts Disrupt Alveolar Epithelial Cell Proliferation and Promote Migration in Wound Healing

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease marked by excessive accumulation of lung fibroblasts (LFs) and collagen in the lung parenchyma. The mechanisms that underlie IPF pathophysiology are thought to reflect repeated alveolar epithelial injury leading to an aberrant wound r...

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Detalles Bibliográficos
Autores principales: Blokland, Kaj E. C., Waters, David W., Schuliga, Michael, Read, Jane, Pouwels, Simon D., Grainge, Christopher L., Jaffar, Jade, Westall, Glen, Mutsaers, Steven E., Prêle, Cecilia M., Burgess, Janette K., Knight, Darryl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238173/
https://www.ncbi.nlm.nih.gov/pubmed/32344567
http://dx.doi.org/10.3390/pharmaceutics12040389