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Senescence of IPF Lung Fibroblasts Disrupt Alveolar Epithelial Cell Proliferation and Promote Migration in Wound Healing
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease marked by excessive accumulation of lung fibroblasts (LFs) and collagen in the lung parenchyma. The mechanisms that underlie IPF pathophysiology are thought to reflect repeated alveolar epithelial injury leading to an aberrant wound r...
Autores principales: | Blokland, Kaj E. C., Waters, David W., Schuliga, Michael, Read, Jane, Pouwels, Simon D., Grainge, Christopher L., Jaffar, Jade, Westall, Glen, Mutsaers, Steven E., Prêle, Cecilia M., Burgess, Janette K., Knight, Darryl A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238173/ https://www.ncbi.nlm.nih.gov/pubmed/32344567 http://dx.doi.org/10.3390/pharmaceutics12040389 |
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