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Recombinant Peptide Production Platform Coupled with Site-Specific Albumin Conjugation Enables a Convenient Production of Long-Acting Therapeutic Peptide

The number of therapeutic peptides for human treatment is growing rapidly. However, their development faces two major issues: the poor yield of large peptides from conventional solid-phase synthesis, and the intrinsically short serum half-life of peptides. To address these issues, we investigated a...

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Detalles Bibliográficos
Autores principales: Bak, Mijeong, Park, Junyong, Min, Kiyoon, Cho, Jinhwan, Seong, Jihyoun, Hahn, Young S., Tae, Giyoong, Kwon, Inchan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238188/
https://www.ncbi.nlm.nih.gov/pubmed/32316169
http://dx.doi.org/10.3390/pharmaceutics12040364