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A Novel Star Like Eight-Arm Polyethylene Glycol-Deferoxamine Conjugate for Iron Overload Therapy

The traditional iron chelator deferoxamine (DFO) has been widely used in the treatment of iron overload disease. However, DFO has congenital disadvantages, including a very short circular time and non-negligible toxicity. Herein, we designed a novel multi-arm conjugate for prolonging DFO duration in...

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Detalles Bibliográficos
Autores principales: Yu, Bohong, Yang, Yinxian, Liu, Qi, Zhan, Aiyan, Yang, Yang, Liu, Hongzhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238202/
https://www.ncbi.nlm.nih.gov/pubmed/32272723
http://dx.doi.org/10.3390/pharmaceutics12040329